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Preimplantation Genetic Screening (PGS) for Aneuploidy with IVF

Preimplantation Genetic Screening (PGS) for Aneuploidy with IVF

Assisted reproductive technology (ART) is a field of medicine for the treatment of infertility. ART assists in the fertilization of the sperm and egg (outside a woman’s body, in a lab), either through in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI). Preimplantation genetic screening (PGS) is a diagnostic tool used to examine embryos formed through these methods, for chromosomal abnormalities, which is the chief cause of miscarriage and embryo implantation failure in the womb. The process is also called aneuploidy screening as it identifies aneuploidy abnormalities, which refers to the presence of an abnormal number of chromosomes.

PGS is recommended for women over 35 years of age with repeated implantation failures, recurrent pregnancy losses, family history of chromosomal problems and partners with male factor infertility.

Your doctor first performs normal IVF procedures, which involves the collection of mature eggs from the ovaries and fertilization with sperm in the lab. The resulting embryos are cultured in the laboratory for two to three days or five to six days, until the embryo has several actively dividing cells. A few cells are removed at this stage and tested for chromosomal abnormalities. The healthy embryos are then transferred into the womb for development, while those with abnormal number of chromosomes are destroyed.

As with any procedure, PGS may involve certain risks and complications such as the probability of having no embryos left for transfer after the screening or the damage of some during the cell removal process. It is important to remember that PGS screening does not guarantee against miscarriages.

  • Mckinney

    McKinney
    6850 TPC Drive , Suite 105
    Unit B
    McKinney, TX 75070

    McKinney

    6850 TPC Drive , Suite 105
    Unit B
    McKinney, TX 75070

  • Grapevine

    Grapevine
    823 Ira E. Woods Avenue
    Grapevine, TX 76051

    Grapevine

    823 Ira E. Woods Avenue
    Grapevine, TX 76051

  • Rockwall

    Rockwall
    935 West Ralph Hall Pkwy
    Suite 103
    Rockwall, TX 75032

    Rockwall

    935 West Ralph Hall Pkwy
    Suite 103
    Rockwall, TX 75032

  • Dallas

    Dallas
    3800 San Jacinto
    Suite 123
    Dallas, TX 75204

    Dallas

    3800 San Jacinto
    Dallas, TX 75204

  • Tyler

    Tyler
    7925 S. Broadway Ave
    Suite 210
    Tyler, TX 75703

    Tyler

    7925 S. Broadway Ave
    Suite 210
    Tyler, TX 75703