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One vs Two IUIs

One vs Two IUIs

Intrauterine insemination (IUI) is a low-cost treatment available to sub fertile couples. The procedure is typically used in combination with ovulation induction medications such as Clomid, Femara or injectables, but can also be used with spontaneous or natural ovulatory cycles. IUI can be performed with a partner sperm (fresh or frozen), or with donor samples (frozen).

Couples are usually encouraged to engage in coitus after intrauterine insemination over the next few days during the fertile period to increase the chances of conception. While intercourse can result in the wastage of most of the sperm (sperm can survive for only 1 hour in the vaginal environment), IUI can effectively deliver millions of motile sperm into the uterine cavity where they can live for 3-4 days. This simple procedure thus can significantly increase the chances of conception per cycle, especially for a woman with closed cervix (as a result of prior cervical surgery) or in cases of sub optimal sperm parameters.

Because fertility can be a numbers game, patients often ask if two IUIs are better than one. Most studies so far have not demonstrated any significant difference in pregnancy rates between one versus two IUIs. In our experience, a single well timed insemination is as effective as two without the added cost of the latter. However, if the total number of motile sperm is less than 1 million during the first IUI, we recommend a second one in the following day.

Due to stress, collection error (spillage) or other factors, the first semen sample may yield low number of motile sperm. We have observed that a second sample collected in the following day can make up for the deficiency and improve the chance of pregnancy.

  • Mckinney

    McKinney
    6850 TPC Drive , Suite 105
    Unit B
    McKinney, TX 75070

    McKinney

    6850 TPC Drive , Suite 105
    Unit B
    McKinney, TX 75070

  • Grapevine

    Grapevine
    823 Ira E. Woods Avenue
    Grapevine, TX 76051

    Grapevine

    823 Ira E. Woods Avenue
    Grapevine, TX 76051

  • Rockwall

    Rockwall
    935 West Ralph Hall Pkwy
    Suite 103
    Rockwall, TX 75032

    Rockwall

    935 West Ralph Hall Pkwy
    Suite 103
    Rockwall, TX 75032

  • Dallas

    Dallas
    3800 San Jacinto
    Suite 123
    Dallas, TX 75204

    Dallas

    3800 San Jacinto
    Dallas, TX 75204

  • Tyler

    Tyler
    7925 S. Broadway Ave
    Suite 210
    Tyler, TX 75703

    Tyler

    7925 S. Broadway Ave
    Suite 210
    Tyler, TX 75703